Bad allergy, cold, or Doxycycline

I am taking 400mg/day of Doxycycline to treat my Lyme Disease.  While I normally have some post-nasal drip due to various allergies, the past few weeks have been really bad on the 'gunk factor'.  On top of that, I have a sore throat a good deal of the time and I sometimes get moderately congested and sneezy.  Last night I thought that I had the beginnings of a cold.  This morning I feel a little better as far as the sneezing and congestion go.

Also, in the last few weeks I have been getting headaches while I am sleeping.  I usually wake up an hour or so before the alarm goes off.  Lately, I've woken to a moderate headache.  I've been taking acetaminophen and then going back to bed to sleep until the alarm goes off.  The headache has been either less annoying or gone when I wake.


I have an appointment with my doctor on Tuesday for a B-12 injection.  I plan on mentioning these annoyances to him at that time.  I have been on the Doxycycline for just over two weeks now.  While I didn't expect to see any improvement to my Lyme symptoms yet, I wasn't expecting these particular side effects.  It's not enough to want me to give up the antibiotic.  I just want to make sure that these are possible side effects and not something else going on.

Cross purpose supplements

My latest set of pill-popping dilemmas involves supplements. 

Until I started taking the antibiotic, I was taking a mineral (calcium/magnesium/zine) supplement at bedtime.  The magnesium was supposed to be helping with some of my muscle pain issues and with some sleep issues.   However, I'm supposed to avoid taking in any calcium for at least two hours after I take my antibiotic.  I have to take one dose of my antibiotic with dinner.  I often go to bed less than two hours after eating dinner, since I get home after 6 most days AND the Adderall makes me unhurried about eating any way.

I had been taking St Johns Wort in the morning, since it doesn't like calcium (which I had been taking at night).  So, the first change I made was to switch those around.  I now take the St Johns Wort at bed and the calcium in the morning, at least an hour before breakfast so that it doesn't interfere with the antibiotic.

I am taking two different probiotics to help make up for the good flora that is being killed off by the antibiotic.  I need to take these on an empty stomach so that they hang around in my system and don't just happily eat the food in my stomach.

I just started taking a supplement (serrapeptase) that helps the antibiotics work by attacking the biofilms that the Lyme spirochettes surround themselves with.  It is yet another pill that I need to take on an empty stomach.  Since I am not sure how it will impact the efficacy of the probiotics I am taking, I'm trying to take them an hour apart from each other.

Also, I try to take my Adderall as soon as I get up in the morning to help wake me up and make sure that it is mostly out of my system by the end of the day.

Basically, this means that I'm taking five pills when I get up and then two pills an hour later.  Which also means that I cannot eat breakfast until at least two hours after I get up.  At that point the Adderall has kicked in, so I may not be all THAT interested in breakfast.  However, I have to have a good sized breakfast to take the antibiotic.  (See previous post on the cross purpose drugs.)

Sometimes I think about the amount of pills I take and remember Joan Cusack's character from the movie "Toys".  Turned out that she was a robot of some sort, but at every meal she would take a bunch of pills and put them between two slices of bread and eat her "sandwich".  Not a very popular movie, so I couldn't find a YouTube clip to share unfortunately.

Cross purpose pharmaceuticals

In order to combat my Lyme disease, I am taking two hefty doses of an antibiotic that must be taken with food.  If you don't have a good amount of food in your stomach it is highly likely that you will vomit.  In addition, I have a powerful NSAID that I should take several times a day that has the same warnings.  That one I have actually experienced twice.  The first time because I assumed that the warning was on the same level as taking Ibuprofen, which I can gobble up on an empty stomach most of the time without any ill effects.  The resulting nausea and vomiting from my mistake taught be a lesson about heading warnings on prescription pharmaceuticals.  The second time it happened it wasn't because I had taken the pill on an empty stomach.  I learned that "with food" meant a SIGNIFICANT amount of food. 

Part of the disease symptoms that I have to deal with is my constant sleepiness, regardless of how much sleep I get.  I went through a sleep study in July that showed that there is nothing abnormal, or 'non restful', with my sleep patterns.  I was labeled with Idiopathic Hypersomnolence (meaning:  no known cause sleepiness).  To fight the sleepiness I started taking Adderall.  It's an amphetamine.  Amphetamines sap your appetite.  Part of me was looking forward to taking this in hopes that it would help me shed some pounds.  Unfortunately, I'm taking several drugs that are at cross purposes.

The Adderall diminishes my appetite.  I can easily skip breakfast when I'm taking it.  On the other hand, I need to eat a reasonably solid breakfast and then dinner to take two of my other drugs.  I have cut down on my snacking quite a bit since starting the Adderall, so I have dropped a couple of pounds.  However, it does kind of stink that I can't take full advantage of one of it's side effects to REALLY drop some weight.

By the way, when I get ready for bed, one of the drugs I take is a muscle relaxant to minimize the stiffness and potential for muscle spasms that can happen when I sleep.  I have actually injured myself, causing inflammation that takes days to weeks to recover from (see yesterday's post about injury recovery).  Usually the Adderall is out of my system by bed time, but the muscle relaxant is at cross purposes to it as well.

"Better living through chemistry" right?

What is your pain level right now?

As a chronic pain sufferer, I am used to answering the following question from medical providers on a regular basis:

On a scale of 1 to 10, what is your pain level right now?

Days like today present a quandary.   It depends on the absolute definition of the word "pain".  (No, no, not "is" or "sex" or "It!") 

Nineteen months ago I slipped on a patch of ice in front of my house and severely damaged the soft tissue in my left shoulder.  Scans showed that there were no tears to any ligaments, tendons, or other mappable structures.  After six months of physical therapy we decided that it was as 'back' as it was going to get.  Unfortunately, this did not leave me with a healthy shoulder.

Part of my chronic health issue over the last seven years has been chronic inflammation.  If I sustain any sort of injury, it seems that I will be plagued by that injury on some level until my dying day.  The left shoulder is a prime example of this scenario.  Every day it at least aches to a certain degree.  Some days it straight out hurts.  Even so, in comparison to other pains that I have struggled with, the chronic shoulder pain rarely merits more than a 7.  However, the shoulder situation is about more than just "pain". 

Usually there is more of a sense of discomfort.  The joint feels swollen in some way.  It can feel better to hold my arm straight up, especially if I bend at the elbow and rest the weight of the arm on my head (nice image, right?  I've gotten some seriously odd stares at the office over this.)  There must be some swelling involved since, at its worse, my left hand feels a bit 'off' and my bicep may feel achy as well.  However, it's not all inflammation since my prescription NSAID only dampens the discomfort a little.  And, it's not strictly pain either, since taking the max dose of my non-opiate prescription pain relievers barely warrants a footnote when the shoulder is really acting up.  Usually both drugs together can  tune the discomfort down a notch or two so that I can get through the day.

USUALLY.  Today is not one of those days. 

If I were to step back and analyze "the pain" in my shoulder right now, it probably would warrant a six.  Right there, in the front of the shoulder.  SIX.  Six isn't that bad, right?

Except it's not just that spot where it definitely "hurts".  It's about all the discomfort in the surrounding tissue, into my bicep, and down to my hand.  THEN, there's the fact that my pelvic girdle is a bit achy today, as is my low back.  On top of that I know that when I get up from this chair, both thighs are going demand my attention with their multiple maddening small to midsized complaints.

It's all additive.  I logically know that all of it together is not as distracting and intolerable as the worse pain that I've ever experienced (tie between gallbladder attack and labor).  Still, when the dozens of bits conspire together you want to be able to quantify the sense that you can barely catch your breath from moment to moment for want of screaming.  Mostly, it's just below that or I wouldn't have been able to write all of this.  Though I did have to stop and refocus myself too many times to count.  Each time I take several deep breaths and try to dispel the cacophony of all those co-conspirators bouncing around in my head.

This is just one example of what it's like to live with chronic pain.  I am so glad that every day is not quite this bad.  Today is one of those days where I contemplate taking up prayer to a deity that I cannot believe in.  Oh, how I wish I could.  If I could pray, I would pray that the Lyme diagnosis and treatment will at least keep the discomfort from reaching this volume  ever again.  I would like to believe that I could make all (or at least most) of the pain go away.  But my skeptical wiring won't even let me hope for something that seems too much like a fairytale.

If you see me and I seem in good spirits, do not assume that it means that I am not in pain.  Also, if I am not showing it, do not ask me about my pain.  When I look fine, I'm doing my best not to think about it.  So please, please, don't remind me.  If I look miserable or distracted, feel free to ask me how I am doing.  Or if I need to talk about it and I trust you enough, I will bring it up. 

The last thing I want is to have my pain define my relationship with others.  Days like today it is hard for even me to remember this, but I am more than this pain that I live with.  Every day.  Every hour.  And sometimes, every minute ... to minute ... to minute.

My muddled mind

In the last year I have become more and more fatigued.  No amount of sleep ever seems to be enough to keep me from being sleepy, or sometimes even nodding off, during the day.  In the last few months, I have found myself being able to remember things.  Mostly it's just the names of things or the names of people.  However, as someone who has always had a great memory for details this turn of events scares the crap out of me.  I am hoping that this is just a side effect of the fatigue and not a symptom all on it's own.  However, memory loss and mind fog are symptoms mentioned on the long list of those associated with Lyme.

In either case, stopping the progression of Lyme should help with both the fatigue and any other neurological issues.  My fear is that some of my symptoms could be permanent.  There's been mention that even if we nip the Lyme progression in the bud, I could still be saddled with the symptoms of Fibromyalgia (which sound an awful lot like Lyme symptoms).  The thinking is that while lots of Fibromyalgia is actually Lyme, people who have had Lyme for a long time may end up with Fibromyalgia even after the spirochetes have been eradicated.